We demonstrated that Treatment with MSG induces a dose-dependent swelling and death of mature neurons (12-14 days in culture) [...]

Boiling MSG does not affect its toxicity but the addition of Vitamin C provides significant protection against MSG toxicity [...]

“MSG is the most recognized and highly debated food additive in the world, and the attitudes regarding its use are very different depending upon which socioeconomic groups or cultures are being polled. It is an interesting dynamic—there is a very strong East/West divide when it comes to views on MSG.”

In newborn mice, MSG induced acute neuronal necrosis in several regions of developing brain.

As adults, treated animals showed stunted skeletal development, marked obesity, and female sterility. Pathological changes were also found in several organs...

People who use monosodium glutamate, or MSG, as a flavor enhancer in their food are more likely than people who don’t use it to be overweight or obese even though they have the same amount of physical activity and total calorie intake [...]

A Calgary researcher is getting ready to publish a groundbreaking study that links a popular food additive to reduced growth in the brain cells of snails — work that could have major implications for children’s health.

Conclusions: These results take on considerable significance in light of the widespread usage of dietary MSG and we suggest that MSG should have its safety profile re-examined and be potentially withdrawn from the food chain.

Conclusions: MSG consumption was positively, longitudinally associated with overweight development among apparently healthy Chinese adults.

Additional studies are needed to elucidate mechanisms of action and to establish causal inference.

Significant accumulation of glutamate in vitreous was observed in rats following addition of sodium glutamate to the diet.

In the retinal morphology, thickness of retinal neuronal layers was remarkably thinner.

Some common substances can cause brain damage by exciting neurons to death. Should they be regulated by the FDA?

J. Olney didn’t success to get the FDA to ban glutamates from children’s food, but food manufacturers voluntary stopped putting MSG into their products.

These studies identified genetically determined differences in MSG consumption in mice and suggested that the metabolic fate of MSG may play an important regulatory role. In addition, they provide the first characterization of genetic variation in amino acid metabolism.